Challenges of Translational Science

How inclusion of genetic counselors on the research team can benefit translational science.

Translational research in medicine is necessarily a team-based endeavor, and, indeed, translational research teams often include researchers from many different disciplines. We outline some of the practical challenges that are particularly salient to translational research, both for scientists and study participants, and propose that genetic counselors--a group of specialty-trained health care ...

New Hopes and Challenges for Treatment of Neurodegenerative Disorders: Great Opportunities for Young Neuroscientists

The Many Meanings of Evidence: Implications for the Translational Science Agenda in Healthcare

Health systems across the world are concerned with the quality and safety of patient care. This includes investing in research and development to progress advances in the treatment and management of individuals and healthcare organisations. The concept of evidence- based healthcare has gained increasing currency over the last two decades; yet questions persist about the time it takes for new re...

A long academic journey.

In this case study, an early-career electrical engineer interviews an established translational biomedical engineer. The discussion covered topics such as challenges associated with the merging of fundamental engineering science with the pursuit of clinically informed research, how best to train engineering students for future innovation, and how to establish international partnerships.

Meeting the governance challenges of next-generation biorepository research.

Advances in clinical translational research have led to an explosion of interest in infrastructure development and data sharing facilitated by biorepositories of specimens and linked health information. These efforts are qualitatively different from the single-center sample collections that preceded them and pose substantial new ethics and regulatory challenges for investigators and institution...

From Knowing to Doing—From the Academy to Practice; Comment on “The Many Meanings of Evidence: Implications for the Translational Science Agenda in Healthcare”

In this commentary, the idea of closing the gap between knowing and doing through closing the gap between academics and practitioners is explored. The two communities approach to knowledge production and use, has predominated within healthcare, resulting in a separation between the worlds of research and practice, and, therefore, between its producers and users. Meaningful collaborations betwee...